GenBank是美國國家衛生研究院(NIH)的基因序列資料庫,是所有公開可用DNA序列的註釋集合(Nucleic Acids Research, 2013 Jan;41(D1):D36-42)。GenBank是國際核苷酸序列資料庫合作組織的一部分,該組織包括日本DNA數據銀行(DDBJ)、歐洲核苷酸檔案(ENA)和美國國家生物資訊中心(NCBI)的GenBank。這三個組織每天交換資料。
GenBank每兩個月發布一次版本,並可從ftp網站上獲取。關於當前版本的GenBank的發布說明提供了有關發布的詳細信息,以及對即將對GenBank進行的更改的通知。以前版本的GenBank的發布說明也是可用的。每個版本都提供了傳統GenBank部門和WGS部門的GenBank增長統計信息。
一個註釋的GenBank樣本記錄,用於Saccharomyces cerevisiae基因,展示了GenBank平面文件格式的許多特點。
訪問GenBank有幾種方式可以搜索和檢索數據。
使用Entrez Nucleotide搜索GenBank的序列識別符號和註釋。
使用BLAST工具搜索和比對GenBank的序列。
GenBank提供了豐富的基因序列資料,使科學家和研究人員能夠尋找、比對和分析特定基因的序列和相關註釋。這對於基因組研究、基因功能研究以及藥物開發等領域非常重要。
(資料來源:NCBI)
折疊內容
GenBank ® is the NIH genetic sequence database, an annotated collection of all publicly available DNA sequences (Nucleic Acids Research, 2013 Jan;41(D1):D36-42).Dec 8, 2022
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GenBank Overview
What is GenBank?
GenBank ® is the NIH genetic sequence database, an
annotated collection of all publicly available DNA sequences
(Nucleic Acids Research, 2013 Jan;41(D1):D36-42). GenBank is part of the
International Nucleotide Sequence Database Collaboration,
which comprises the DNA DataBank of Japan (DDBJ), the European
Nucleotide Archive (ENA), and GenBank at NCBI. These three
organizations exchange data on a daily basis.
A GenBank release occurs every two months and is available from the
ftp site. The release notes
for the current version of GenBank provide
detailed information about the release and notifications of upcoming
changes to GenBank. Release notes for previous GenBank releases
are also available. GenBank growth
statistics for both the traditional GenBank divisions
and the WGS division are available from each release.
An annotated sample GenBank record for a
Saccharomyces cerevisiae gene demonstrates many of the features of
the GenBank flat file format.
Access to GenBank
There are several ways to search and retrieve data from GenBank.
Search GenBank for sequence identifiers and annotations with
Entrez Nucleotide.
Search and align GenBank sequences to a query seque
Read More: What is the database for finding genes?